With Reactive Arthritis and Systemic Lupus-UTI’s are common. So is inflammation in your kidneys (glomerular nephritis), bladder (interstitial cystitis), and pretty much any mixed connective tissue anywhere is fair game.
After many years of being in remission from lupus nephritis (chronic kidney disease stage 3b)- I seem to be having issues again. My doc thinks kidney infection but I’m not convinced. With lupus it’s possible to have a crazy amount of white blood cells in your urine but no signs of infection (fever, vomiting, no nitrates or bacteria in your urine, etc) and that can mean simply destructive inflammation.
In cases like mine (and I’m certainly not alone with this issue) -further testing is indicated. That flank pain and lower pelvic pressure can have several causes. This coming up week I’ll have a cat scan and kidney biopsy and that will tell us more.
So if your having many UTI’s without bacteria showing up-your likely looking at inflammation!
Here’s some info on pelvic inflammatory conditions:
Interstitial Cystitis Facts:
PBS/IC is an inflammatory disease of the bladder that can cause ulceration and bleeding of the bladder’s lining and can lead to scarring and stiffening of the bladder.The symptoms of PBS/IC are pelvic pain as well as urinary frequency and urgency.
PBS/IC has a variable clinical course, meaning that symptoms can appear and disappear over time. Moreover, the intensity of symptoms varies among individuals and even within the same individual over time.
The cause of PBS/IC is unknown, but abnormalities in the leakiness or structure of the lining of the bladder are believed to play a role in the development of PBS/IC.
The diagnosis of PBS/IC is based on the symptoms, an abnormal potassium sensitivity test (PST), and elimination of other conditions that may be responsible for the symptoms.
Treatment for PBS/IC most commonly utilizes heparinoid drugs to help restore integrity of the bladder lining along with other oral medications. Bladder distension and intravesical drug therapy are other treatments that may provide relief in PBS/IC.
Kidney Inflammation Facts:
There are different kinds of kidney inflammation. Here are a few from Healthline.com:
Think of your kidneys as your body’s filters, a sophisticated waste removal system comprised of two bean-shaped organs. Every day, your hard working kidneys process 200 quarts of blood in a day and remove two quarts of waste products and excess water. If the kidneys suddenly become inflamed, you will develop a condition called acute nephritis. Acute nephritis has several causes and can lead to kidney
In interstitial nephritis, the spaces between the renal tubules that form urine become inflamed. The kidneys swell from the inflammation.
Pyelonephritis is an infection in the bladderthat travels up the ureters and spreads into the kidneys. Ureters are two tubes that transport urine from each kidney to the bladder, the muscular organ that holds urine until it passes out of the body through the urethra.
This type of acute nephritis produces inflammation in the glomeruli. Glomeruli are the tiny capillaries that transport blood and behave as filtering units. Damaged and inflamed glomeruli may not filter the blood properly.
In any case, with autoimmune disease be aware of your symptoms, get regular urinalysis and blood work done, and see your doctor regularly. 🙂
Here’s a good video on Glomerulonephritis-